WebApr 8, 2013 · In older patients discharged from acute care hospitals, the use of high-dose PPIs is associated with increased 1-year mortality. Randomized controlled studies … WebMar 19, 2024 · In-hospital mortality from SBP is estimated at 11–67% . SBP is exacerbated by the frequent use of proton pump inhibitors (PPIs) in cirrhotic patients with ascites, leading to a reduction in gastric acidity and an increase in intestinal permeability which promotes bacterial translocation and colonization of mesenteric lymph nodes [ 5 ].
PPI use and risk of death – cause for concern?
WebMany observational studies have evaluated the associations between PPI use and mortality, but the results were conflicting . For example, a cohort study of 0.21 million participants … WebFeb 17, 2024 · The association between proton pump inhibitors (PPIs) and increased mortality may be explained, in part, by protopathic bias. These findings, from an analysis of an incident drug user cohort, were published in Clinical Gastroenterology and Hepatology. Investigators analyzed a random sample (n=840,565) of all prescription and encounter … cheero モバイルバッテリー 評判
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WebSep 16, 2024 · The PPI group had a significantly higher 90-day mortality than the H2RA group (relative risk: 1.28; P = 0.01). However, no significant inter-group differences in the risk of clinically important ... WebJul 23, 2024 · Results were published July 12 by the British Journal of Cancer. Overall, 4,746 (14.0%) patients died, with an adjusted HR of 1.38 (95% CI, 1.32 to 1.44) for all-cause mortality among PPI users compared with PPI nonusers. Stronger associations were found among men, patients with cancer stage 0 to 1, those with rectal cancer, and those … WebJun 20, 2024 · During a median follow-up of 10 years, about 45.5 excess deaths occurred per 1000 PPI users (18, 13, 6, and 4 excess deaths attributed to circulatory system diseases, neoplasms, genitourinary system diseases, and infectious diseases, respectively). Duration of PPI use was associated linearly with all-cause death. cheer up sports 県民招待事業 ファジアーノ岡山