Splet27. jul. 2024 · As a proof of principle that the PDGFRβ - P2A - CreER T2 mouse line is an efficient tool to drive genetic modifications in perivascular cells, we used it to specifically … SpletIt can be classified into cells positive for vascular endothelial growth factor receptor 2 (VEGFR2 or FLK1) or platelet-derived growth factor receptor α (PDGFRα), representing lateral and paraxial mesoderm, respectively. Era and colleagues generated knock-in mice carrying GFP-Cre-ERT2 at the start codon of Pdgfra [1]. They confirmed Cre ...
PDGFRβ-P2A-CreERT2 mice: a genetic tool to target pericytes in ...
SpletPDGFRβ-P2A-CreER T2 mice: a genetic tool to target pericytes in angiogenesis PDGFRβ-P2A-CreER T2 mice: a genetic tool to target pericytes in angiogenesis Angiogenesis. … cb溶接 とは
PDGFRb+ mesenchymal cells, but not NG2+ mural cells, contribute …
Splet14. sep. 2016 · We report that Pdgfrα-CreERT2 transgenic mice are highly suitable for OPC-directed gene recombination in the CNS, can be used to achieve robust recombination in OPCs, induce moderate recombination in PDGFRα + bone marrow stromal cells, and have a minimal effect on other PDGFRα + cell populations. Materials and Methods Transgenic … SpletThis gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet … Splet15. nov. 2004 · FIP1L1-PDGFRA is a relatively infrequent but treatment-relevant mutation in primary eosinophilia that is indicative of an underlying systemic mastocytosis. Subjects: Clinical Trials and Observations, Neoplasia, Oncogenes and Tumor Suppressors Topics: cb溶接 継手位置 イモ