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List of platinum based chemotherapy agents

WebL01XA — Platinum compounds. Drugs. Drug. Drug Description. Cisplatin. A platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors. Nedaplatin. Used in the treatment of non-small cell lung cancer, small cell lung cancer, oesophygeal cancer, and head and neck cancers . Oxaliplatin. WebSingle new agents reportedly produce promising response and survival effects, but platinum-based doublets remain the standard chemotherapy for advanced non-small-cell lung cancer (NSCLC). The aim of this study was to evaluate the effectiveness of platinum for advanced NSCLC by carrying out a meta-analysis of trials that compared platinum …

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WebPlatinum-based agents are important drugs or drug candidates for cancer chemotherapy. Traditional platinum drugs including the globally approved cisplatin, carboplatin and … WebPlatinum. Cisplatin; Carboplatin; Dicycloplatin; Eptaplatin; Lobaplatin; Miriplatin; Nedaplatin; Oxaliplatin; Picoplatin; Satraplatin; Triplatin tetranitrate; These agents also bind at N7 of … highland cleveland clinic https://aurorasangelsuk.com

Platinum-based drugs: past, present and future - PubMed

Web14 apr. 2024 · Among 485 patients treated with first-line platinum-based chemotherapy, the probability of initiating maintenance avelumab increased over time following approval . In the 22 months after FDA approval, 99 of 485 patients (20.4%) treated with first-line chemotherapy and 78 of 321 maintenance-eligible patients (24.3%) received … Web1 mei 2024 · Platinum complex drugs commonly used in chemotherapy as anticancer agents. Pt chemotherapeutics make up roughly 50% of all chemotherapeutic drug regimens. Platinum drugs are used in both Pt (II) and Pt (IV) oxidation states. Pt antitumor complexes have at least three components in common: WebCarboplatin is a chemotherapy drug used for treatment of many types of cancer. The U.S. Food and Drug Administration approved carboplatin for use treating patients with ovarian and non-small cell lung cancer, and oncologists often use carboplatin "off-label" for other cancers. Testicular, stomach, and bladder cancers are among those treated ... highland climates are most affected by what

Risk of Leukemia after Platinum-Based Chemotherapy for Ovarian Cancer

Category:Cytotoxic drugs Treatment summaries BNF NICE

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List of platinum based chemotherapy agents

Platinum-containing regimens for metastatic breast cancer

Web5 okt. 2024 · Out of 42 patients diagnosed with advanced non-resectable NSCLC who were treated with platinum-based chemotherapy or had symptoms treated, we extracted 42 cases with complete follow up. This included 17 individuals who received symptoms treatment only (natural history, NH, cohort) and 25 patients who underwent platinum … Web2 aug. 2024 · Taxane agents are used in the treatment of breast, gynecologic, prostate, head and neck, and lung cancers, and include paclitaxel, docetaxel, nab-paclitaxel, and cabazitaxel (Table 1) [ 15 ]. Paclitaxel (Taxol) was originally isolated from the bark of the Pacific yew tree, while docetaxel (Taxotere) was made from a semisynthetic process [ 15 ].

List of platinum based chemotherapy agents

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Web20 mei 2008 · 19088 Background: Single-agent chemotherapy as a first-line treatment is currently considered as the standard approach for elderly patients with advanced NSCLC. Since the platinum-based combination chemotherapy is the standard treatment for younger patients with advanced NSCLC, it may also have more effective for elderly. We … Web15 mei 2024 · The platinum-based drugs cisplatin, carboplatin and oxaliplatin are regularly prescribed in the treatment of cancer and while they are effective, their use is …

Web3 mrt. 2008 · Unfortunately, resistance has limited the efficacy of these agents in most diseases. Resistance to platinum-based chemotherapy can be intrinsic or acquired and may be mediated by factors outside or within the cancer cell or at its cell membrane. Resistance to platinum chemotherapy is multifactorial (2–6). Web12 sep. 2024 · Each of the platinum coordination complexes is described separately with specific references. General references to their pharmacology and hepatotoxicity are given after this introductory …

WebThe chemo drugs may be given on one or more days in each cycle. Chemo drugs used to treat endometrial cancer may include: Paclitaxel (Taxol ®) Carboplatin. Doxorubicin (Adriamycin ®) or liposomal doxorubicin (Doxil ®) Cisplatin. Docetaxel (Taxotere ®) Most often, 2 or more drugs are combined for treatment. Web28 mrt. 2024 · Zejula is indicated: • as monotherapy for the maintenance treatment of adult patients with advanced epithelial (FIGO Stages III and IV) high-grade ovarian, fallopian tube or primary peritoneal cancer who are in response (complete or partial) following completion of first-line platinum-based chemotherapy.

Web16 mrt. 2024 · We read with great interest the letter by Poggio et al.,1 updating their previous meta-analysis on the role of platinum compounds in neoadjuvant chemotherapy (NAC) of triple-negative breast cancer (TNBC).2 The current results indicate that adding a platinum agent significantly increases event-free survival (EFS) but not overall survival …

Web10 nov. 2024 · Thus, associated with the use of platinum agents, expressed regression of the tumor process was observed in 36% of patients, compared with 14.9% of patients against the non-platinum chemotherapy. The results of linear regression analysis confirmed the statistical significance of this finding. how is bowel babeWeb13 apr. 2024 · Eighty-nine percent of patients previously received androgen-signaling inhibitor(s), 68% had platinum-based chemotherapy, and 50% had prior taxane chemotherapy. The median duration of follow-up was 30.8 weeks (range, 1.9-86.9), and the median duration of treatment was 9 weeks (range, 0.7-63). highland climate temperatureWeb1 jun. 2016 · This list of chemotherapeutic agents covers the cancers each drug is used for, as well as the recommended dosage and possible toxicities of the therapy. ... Non–small-cell lung cancer with progression on or after a platinum-based chemotherapy. Dosage: 3 mg/kg every 2 weeks. how is box 16 on w2 calculatedWeb1 apr. 2024 · Platinum-based chemotherapy regimens have been proven to be effective in various cancers; however, considerable toxicities may develop and can even lead to treatment discontinuation. Diverse factors may influence adverse treatment events, with pharmacogenetic variations being one prime example. Polymorphisms within the … highland climate typeWeb21 sep. 2016 · Randomized phase II and III clinical trials comparing first-line palliative platinum-based chemotherapy with the same regimen without platinum or with platinum replaced by a nonplatinum agent were identified by electronic searches of Medline, Embase, and Cancerlit, and hand searches of relevant abstract books and reference lists. how is box 12 dd calculatedWebNSCLC is the leading cause of cancer-related death in the US. Patients with NSCLC are mostly treated with platinum-based chemotherapy, often in combination with radiation … how is box 12 calculated on w2WebAsk a cancer patient and another use for platinum might come to mind – chemotherapy drugs. Platinum based chemotherapy is used to treat a variety of cancers and most often involves drugs like cisplatin, which is usually given as a drip into your bloodstream. These drugs work to destroy rapidly multiplying cells, like cancer cells. how is bowel cancer treated